Journal article
Body mass index and age at natural menopause: an international pooled analysis of 11 prospective studies
D Zhu, HF Chung, N Pandeya, AJ Dobson, D Kuh, SL Crawford, EB Gold, NE Avis, GG Giles, F Bruinsma, HO Adami, E Weiderpass, DC Greenwood, JE Cade, ES Mitchell, NF Woods, EJ Brunner, MK Simonsen, GD Mishra
European Journal of Epidemiology | SPRINGER | Published : 2018
Abstract
Current evidence on the association between body mass index (BMI) and age at menopause remains unclear. We investigated the relationship between BMI and age at menopause using data from 11 prospective studies. A total of 24,196 women who experienced menopause after recruitment was included. Baseline BMI was categorised according to the WHO criteria. Age at menopause, confirmed by natural cessation of menses for ≥ 12 months, was categorised as < 45 years (early menopause), 45–49, 50–51 (reference category), 52–53, 54–55, and ≥ 56 years (late age at menopause). We used multinomial logistic regression models to estimate multivariable relative risk ratios (RRRs) and 95% confidence intervals (CI)..
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Awarded by Economic and Social Research Council
Funding Acknowledgements
InterLACE project is funded by the Australian National Health and Medical Research Council Project Grant (APP1027196). GDM is supported by Australian National Health and Medical Research Council Principal Research Fellowship (APP1121844). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.