Journal article
PROGRESS: Perindopril protection against recurrent stroke study: Status in March 1997
J Chalmers, S MacMahon, MG Bousser, J Cutler, G Donnan, L Hansson, S Harrap, LS Liu, G Mancia, R Sega, J Menard, J Reid, A Rodgers, C Warlow
JOURNAL OF HUMAN HYPERTENSION | NATURE PUBLISHING GROUP | Published : 1998
Abstract
MAIN OBJECTIVE: The study has been designed to assess the efficacy of blood pressure (BP) reduction in the prevention of stroke in patients with a history of ischaemic stroke, haemorrhagic stroke, or transient ischaemic attack. STUDY DESIGN: A randomised, double-blind, placebo-controlled, international, multicentre trial of the angiotensin-converting enzyme (ACE) inhibitor perindopril, alone or in combination with the diuretic indapamide, in the secondary prevention of stroke and other major cardiovascular events. METHODOLOGY: A total of 6000 normotensive or hypertensive patients with a history of stroke or transient cerebral ischaemia within the previous 5 years will be included in the stud..
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