Journal article

Long-term outcomes of single-ventricle palliation for pulmonary atresia with intact ventricular septum: Fontan survivors remain at risk of late myocardial ischaemia and death

Patrick Elias, Chin Leng Poh, Karin du Plessis, Diana Zannino, Kathryn Rice, Dorothy J Radford, Andrew Bullock, Gavin R Wheaton, David S Celermajer, Yves d'Udekem

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY | OXFORD UNIV PRESS INC | Published : 2018

Abstract

OBJECTIVES: The specific outcomes of patients with pulmonary atresia with intact ventricular septum late after Fontan palliation are unknown. Patients with smaller right ventricles and myocardial sinusoids are known to have worse survival in the first years of life. Whether the potential for coronary ischaemia affects the long-term outcomes of these patients after Fontan palliation is still unknown. METHODS: All patients with pulmonary atresia with intact ventricular septum who underwent the Fontan procedure from 1984 to 2016 in Australia and New Zealand were identified, and preoperative, perioperative and follow-up data were collected. RESULTS: Late follow-up data were available for 120 pat..

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Grants

Awarded by National Health and Medical Research Council (NHMRC)


Awarded by National Heart Foundation Australia Program


Awarded by NHMRC


Funding Acknowledgements

This work was supported by a National Health and Medical Research Council (NHMRC) Partnership Grant [1076849]. The contents of the published material are solely the responsibility of the individual authors. Yves d'Udekem is a Career Development Fellow of The National Heart Foundation Australia Program [CR 10M 5339] and NHMRC Clinician Practitioner Fellow [1082186].