Analysis of Peripapillary Atrophy in Relation to Macular Geographic Atrophy in Age-Related Macular Degeneration.
Petrus Chang, Anna Tan, Glenn J Jaffe, Monika Fleckenstein, Frank G Holz, Steffen Schmitz-Valckenberg, undefined GAP Study Group
Invest Ophthalmol Vis Sci | Association for Research in Vision and Ophthalmology (ARVO) | Published : 2016
PURPOSE: The purpose of this study was to investigate the presence, configuration, and progression of peripapillary atrophy (PPA) relative to macular geographic atrophy (GA) in AMD. METHODS: Confocal scanning laser ophthalmoscopy images of 413 eyes of 413 patients with GA secondary to AMD (median age, 77.0 years) were evaluated for the presence and configuration of PPA at baseline. In addition, the progression of PPA and the regression of the shortest linear dimension between PPA and GA ("buffer zone") were assessed in 164 eyes that had completed 12 months of follow-up. RESULTS: At baseline, PPA was present in 357 (86.4%) of 413 eyes, of which 330 eyes (79.9%) were classified as nonconfluent..View full abstract