Longitudinal analysis of reticular drusen associated with geographic atrophy in age-related macular degeneration.
Julia S Steinberg, Jasmin Auge, Glenn J Jaffe, Monika Fleckenstein, Frank G Holz, Steffen Schmitz-Valckenberg, undefined GAP Study Group
Invest Ophthalmol Vis Sci | Association for Research in Vision and Ophthalmology (ARVO) | Published : 2013
PURPOSE: To characterize longitudinal changes of reticular drusen (RDR) in subjects with geographic atrophy (GA) secondary to age-related macular degeneration in the multicenter, prospective natural history Geographic Atrophy Progression Study. METHODS: Three-field confocal scanning laser ophthalmoscopy fundus autofluorescence (cSLO FAF, excitation [exc.] = 488 nm; emission [em.] 500-800 nm, Heidelberg Retina Angiograph/Spectralis) of 44 eyes of 22 patients with RDR (median age 77.6 years; range, 61-90 years) at baseline were identified in the study population and included for further analysis. Two independent readers determined the presence, topographic distribution, and pattern of RDR at b..View full abstract