Journal article

Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation

Benjamin Faustin, Lydia Lartigue, Jean-Marie Bruey, Frederic Luciano, Eduard Sergienko, Beatrice Bailly-Maitre, Niels Volkmann, Dorit Hanein, Isabelle Rouiller, John C Reed

Molecular Cell | CELL PRESS | Published : 2007

DOI: 10.1016/j.molcel.2007.01.032

Grants

Awarded by NCI NIH HHS

Awarded by NIAID NIH HHS

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Keywords

Inflammation
Magnesium
Kinetics
Adaptor Proteins, Signal Transducing
Complexes
Procaspase-9
Mice
Generation
Acetylmuramyl-Alanyl-Isoglutamine
Baculoviridae
Inhibitor
Enzyme Activation
Caspase 1
Life Sciences & Biomedicine
Science & Technology
Pyrin
Protein Structure, Quaternary
Biochemistry & Molecular Biology
Enzyme
Electron-Microscopy
Apoptosome
Cell Biology
Microscopy, Electron
Ligands
Adenosine Triphosphate
Protein