The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation
Bernardo S Franklin, Lukas Bossaller, Dominic De Nardo, Jacqueline M Ratter, Andrea Stutz, Gudrun Engels, Christoph Brenker, Mark Nordhoff, Sandra R Mirandola, Ashraf Al-Amoudi, Matthew S Mangan, Sebastian Zimmer, Brian G Monks, Martin Fricke, Reinhold E Schmidt, Terje Espevik, Bernadette Jones, Andrew G Jarnicki, Philip M Hansbro, Patricia Busto Show all
Nature Immunology | NATURE PUBLISHING GROUP | Published : 2014
Awarded by Deutsche Forschungsgemeinschaft
Awarded by US National Institutes of Health
We thank C. Tiberi and P.-I. Chiang for technical support. Supported by Deutsche Forschungsgemeinschaft (SFB670 to E.L.), the US National Institutes of Health (R01-HL093262, R01-HL112661 and R01-AI083713 to E.L.), the Alexander von Humboldt Foundation (B.S.F.), intramural BONFOR research support at the University of Bonn (B.S.F.), the European Research Council (Advanced Grant to A.A.), the European Union (NEURINOX to A.A.), the Swiss National Foundation (Sinergia grant to A.A.), the Novartis Research Foundation (A.A.), the Clinical Research Priority Programs "Small RNAs" and "Mechanisms of Human Hemato-Lymphatic Diseases" of the University of Zurich (A.A.), the ImmunoSensation cluster of Excellence in Bonn (E.L.) and the German Center for Infection Research (E.L.).