Journal article

Psychomotor Speed and Functional Brain MRI 2 Years After Completing a Physical Activity Treatment

Caterina Rosano, Vijay K Venkatraman, Jack Guralnik, Anne B Newman, Nancy W Glynn, Lenore Launer, Christopher A Taylor, Jeff Williamson, Stephanie Studenski, Marco Pahor, Howard Aizenstein

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES | OXFORD UNIV PRESS INC | Published : 2010

Abstract

BACKGROUND: Short-term adherence to physical activity (PA) in older adults improves psychomotor processing abilities and is associated with greater brain activation. It is not known whether these associations are also significant for longer-term adherence to moderate-intensity activities. METHODS: We measured the cross-sectional association of regular walking with brain activation while performing the digit symbol substitution test (DSST). Participants of the lifestyle interventions and independence for elders-pilot study were examined 2 years after completing a 1-year treatment, consisting of either PA or education in successful aging (SA). Data were obtained from 20 PA participants who rep..

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Funding Acknowledgements

This work was supported in part by the Intramural Research program and the National Institute on Aging, National Institutes of Health. Dr. Rosano is a Pepper Scholar (1P30 AGO24827-01) and Beeson Scholar (K23AG028966-01) and is supported by the National Institute on Aging (grant numbers RO3 AG025076-02 and R01 AG029232).