Journal article

Identification and Characterization of Microsatellite Markers Derived from the Whole Genome Analysis of Taenia solium

Monica J Pajuelo, Maria Eguiluz, Eric Dahlstrom, David Requena, Frank Guzman, Manuel Ramirez, Patricia Sheen, Michael Frace, Scott Sammons, Vitaliano Cama, Sarah Anzick, Dan Bruno, Siddhartha Mahanty, Patricia Wilkins, Theodore Nash, Armando Gonzalez, Hector H Garcia, Robert H Gilman, Steve Porcella, Mirko Zimic

PLOS NEGLECTED TROPICAL DISEASES | PUBLIC LIBRARY SCIENCE | Published : 2015

Abstract

BACKGROUND: Infections with Taenia solium are the most common cause of adult acquired seizures worldwide, and are the leading cause of epilepsy in developing countries. A better understanding of the genetic diversity of T. solium will improve parasite diagnostics and transmission pathways in endemic areas thereby facilitating the design of future control measures and interventions. Microsatellite markers are useful genome features, which enable strain typing and identification in complex pathogen genomes. Here we describe microsatellite identification and characterization in T. solium, providing information that will assist in global efforts to control this important pathogen. METHODS: For g..

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University of Melbourne Researchers

Grants

Awarded by Fogarty International Center/NIH


Awarded by Medical Research Council


Awarded by FOGARTY INTERNATIONAL CENTER


Funding Acknowledgements

This work was partially supported by the Fogarty International Center/NIH Training Grants D43TW001140 and D43TW006581. HHG. is supported by a Wellcome Trust Senior International Research Fellowship in Public Health and Tropical Medicine. The funders had no role in study design, data collection and analysis or interpretaion; in writing the report or in the decision to submit this manuscript for publication.