Identification and Characterization of Microsatellite Markers Derived from the Whole Genome Analysis of Taenia solium
Monica J Pajuelo, Maria Eguiluz, Eric Dahlstrom, David Requena, Frank Guzman, Manuel Ramirez, Patricia Sheen, Michael Frace, Scott Sammons, Vitaliano Cama, Sarah Anzick, Dan Bruno, Siddhartha Mahanty, Patricia Wilkins, Theodore Nash, Armando Gonzalez, Hector H Garcia, Robert H Gilman, Steve Porcella, Mirko Zimic
PLOS NEGLECTED TROPICAL DISEASES | PUBLIC LIBRARY SCIENCE | Published : 2015
BACKGROUND: Infections with Taenia solium are the most common cause of adult acquired seizures worldwide, and are the leading cause of epilepsy in developing countries. A better understanding of the genetic diversity of T. solium will improve parasite diagnostics and transmission pathways in endemic areas thereby facilitating the design of future control measures and interventions. Microsatellite markers are useful genome features, which enable strain typing and identification in complex pathogen genomes. Here we describe microsatellite identification and characterization in T. solium, providing information that will assist in global efforts to control this important pathogen. METHODS: For g..View full abstract
Awarded by Fogarty International Center/NIH
Awarded by Medical Research Council
Awarded by FOGARTY INTERNATIONAL CENTER
This work was partially supported by the Fogarty International Center/NIH Training Grants D43TW001140 and D43TW006581. HHG. is supported by a Wellcome Trust Senior International Research Fellowship in Public Health and Tropical Medicine. The funders had no role in study design, data collection and analysis or interpretaion; in writing the report or in the decision to submit this manuscript for publication.