Journal article

Immunogenicity of infectious pathogens and vaccine antigens

Siddhartha Mahanty, Antoine Prigent, Olivier Garraud

BMC Immunology | BMC | Published : 2015

Abstract

The concept of the immunogenicity of an antigen is frequently encountered in the context of vaccine development, an area of intense interest currently due to the emergence or re-emergence of infectious pathogens with the potential for worldwide spread. However, the theoretical notion of immunogenicity as discussed in older textbooks of immunology needs reconsideration due to advances in our understanding of immunologic responses. Immunogenicity is a property that can either be a desirable attribute, for example in the generation of an effective protective immunity against infectious pathogens or an undesirable trait, for example when it relates to novel therapeutic compounds and drugs, where..

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University of Melbourne Researchers