Journal article

Polymyxins and Analogues Bind to Ribosomal RNA and Interfere with Eukaryotic Translation in Vitro

Lisa S McCoy, Kade D Roberts, Roger L Nation, Philip E Thompson, Tony Velkov, Jian Li, Yitzhak Tor

ChemBioChem | WILEY-V C H VERLAG GMBH | Published : 2013

DOI: 10.1002/cbic.201300496

University of Melbourne Researchers

Grants

Awarded by National Institutes of Health

Funding Acknowledgements

We thank Dr. Hermann's laboratory for the help with in vitro translation assays and the National Institutes of Health for support (grant GM069773 to Y.T.).

Citation metrics

20Web of Science
19Scopus

Keywords

Fluorescence Resonance Energy Transfer
Rna
Anti-Bacterial Agents
Life Sciences & Biomedicine
Antibiotics
Outer-Membrane
Bad Bugs
Drugs
Specificity
Polymyxin B
Protein Biosynthesis
Translation
Aminoglycoside Antibiotics
Rna, Ribosomal
Chemistry, Medicinal
Science & Technology
Infectious-Diseases-Society
Colistin
Polymyxins
Binding Sites
Recognition
Pharmacology & Pharmacy
Bacteria
Biochemistry & Molecular Biology
Fluorescent Dyes
Streptomycin
Antimicrobial Peptides