Antigen presenting cell-targeted proinsulin expression converts insulin-specific CD8( ) T-cell priming to tolerance in autoimmune-prone NOD mice

Grants

Funding Acknowledgements

Studies were supported by funding from JDRF (32-2008-250, RJS), NHMRC (GNT1043315, RJS), MRC (G0901155, FSW). RJS was recipient of an ARC Future Fellowship (FT110100372). EEH-W was a recipient of a JDRF Career Development Award (2-2013-34). PLSR was a recipient of an Australian Postgraduate Award. RJS is guarantor for this article. We thank Professor Leonard Harrison (WEHI) for providing mice. The authors gratefully acknowledge the NIH Tetramer Core Facility (contract HHSN272201300006C) for provision of (MHC I) tetramers.