Journal article
Alternative regimens of magnesium sulfate for treatment of preeclampsia and eclampsia: a systematic review of non-randomized studies
JJ Pratt, PS Niedle, JP Vogel, OT Oladapo, M Bohren, O Tuncalp, AM Gulmezoglu
Acta Obstetricia et Gynecologica Scandinavica | Wiley | Published : 2016
DOI: 10.1111/aogs.12807
Abstract
Introduction The optimal dosing regimen of magnesium sulfate for treating preeclampsia and eclampsia is unclear. Evidence from the Cochrane review of randomized controlled trials (RCTs) was inconclusive due to lack of relevant data. Material and methods To complement the evidence from the Cochrane review, we assessed available data from non-randomized studies on the comparative efficacy and safety of alternative magnesium sulfate regimens for the management of preeclampsia and eclampsia. Sources included Medline, EMBASE, Popline, CINAHL, Global Health Library, African Index Medicus, Biological abstract, BIOSIS and reference lists of eligible studies. We selected non-randomized study designs..
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Funding Acknowledgements
This work represents the views of the named authors only and does not represent the views of the World Health Organization. This work was financially supported by the World Health Organization and a grant from Merck for Mothers. The funders were not involved in the design, data collection, analysis, interpretation or writing of this report, or in the decision to submit the article for publication.