Australian Case-Control Study of Adverse Reactions to Japanese Encephalitis Vaccine.
P Robinson, T Ruff, R Kass
J Travel Med | Published : 1995
Background: Japanese encephalitis (JE) is widely distributed in Asia and is the world's most common aborviral encephalitis. An effective vaccine against JE has been used in Asia for decades without reports of serious adverse reactions. Since 1989, an apparent increase in frequency of allergic reactions to JE vaccine has been reported from a number of nonendemic countries, including Australia. The objective of this study was to evaluate possible risk factors for allergic reactions associated with Japanese encephalitis (JE) vaccine. Methods: A case-control study was carried out in Australia. Subjects were persons who had developed an allergic reaction (rash and/or edema) that had occurred with..View full abstract