Is 'gamma' (40 Hz) synchronous activity disturbed in patients with traumatic brain injury?
Shameran Slewa-Younan, Alisa M Green, Ian J Baguley, Kim L Felmingham, Albert R Haig, Evian Gordon
Clinical Neurophysiology | Published : 2002
OBJECTIVES: The objective of this work is to determine whether Gamma (40 Hz) synchronous activity has disturbed patients with severe traumatic brain injury (TBI). METHODS: Using a conventional auditory oddball paradigm, the extent of Gamma synchrony across multiple scalp sites in specific frequency bands as a function of time was examined in 15 patients with severe TBI and 15 age- and sex-matched controls. Averaged Gamma synchrony was analyzed using within and between group multiple analyses of variance with region (left versus right hemisphere, anterior versus posterior region) as the within factor. RESULTS: Compared to controls, subjects with TBI displayed significantly delayed early Gamma..View full abstract