The 1996 pertussis epidemic in New Zealand: vaccine effectiveness.
TA Blakely, O Mansoor, M Baker
The New Zealand Medical Journal | Published : 1999
AIM: To assess if reduced vaccine effectiveness may have accounted for increased hospitalisations in the 1996 pertussis epidemic. METHODS: Vaccine effectiveness was estimated by comparing vaccine coverage of the population (derived from a literature review) with that of cases (from notification data available from 1 June 1996) -- the screening method. Only three doses of pertussis vaccine were in the immunisation schedule until 1996, so vaccine effectiveness was calculated for three or more doses. RESULTS: Most likely estimates of vaccine effectiveness for Europeans were 88% (95% confidence interval 71 to 95%) for 5- to 14-month-olds, 80% for 15-month to 4-year-olds (66 to 88%) but lower for..View full abstract