Journal article

Rapid Global Spread of wRi-like Wolbachia across Multiple Drosophila

Michael Turelli, Brandon S Cooper, Kelly M Richardson, Paul S Ginsberg, Brooke Peckenpaugh, Chenling X Antelope, Kevin J Kim, Michael R May, Antoine Abrieux, Derek A Wilson, Michael J Bronski, Brian R Moore, Jian-Jun Gao, Michael B Eisen, Joanna C Chiu, William R Conner, Ary A Hoffmann

CURRENT BIOLOGY | CELL PRESS | Published : 2018

Abstract

Maternally transmitted Wolbachia, Spiroplasma, and Cardinium bacteria are common in insects [1], but their interspecific spread is poorly understood. Endosymbionts can spread rapidly within host species by manipulating host reproduction, as typified by the global spread of wRi Wolbachia observed in Drosophila simulans [2, 3]. However, because Wolbachia cannot survive outside host cells, spread between distantly related host species requires horizontal transfers that are presumably rare [4-7]. Here, we document spread of wRi-like Wolbachia among eight highly diverged Drosophila hosts (10-50 million years) over only about 14,000 years (5,000-27,000). Comparing 110 wRi-like genomes, we find ≤0...

View full abstract

University of Melbourne Researchers

Grants

Awarded by NIH


Awarded by NHMRC


Awarded by USDA SCRI grant


Awarded by NSFC grant


Awarded by NATIONAL CENTER FOR RESEARCH RESOURCES


Awarded by NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES


Funding Acknowledgements

We thank Huong Nguyen, On Yeung Li, Jasmine Osei-Enin, and Kelsey Ortega for help with laboratory experiments; David Begun, Charles Langley, Kristian Stevens, and Li Zhao for help with bioinformatics; and three reviewers for constructive comments. Our work was supported by NIH grants R01GM104325 (M.T., A.A.H.), R35GM124701 (B.S.C.), and S10RR029668 and S10RR027303 (Vincent J. Coates Genomics Sequencing Laboratory at UC Berkeley); a program grant, 1037003, and fellowship, 1118640, from NHMRC (A.A.H.); an investigator award from HHMI (M.B.E.); USDA SCRI grant 63513 (J.C.C.); and NSFC grant 31572238 (J.-J.G.).