Short-Term Interferential Transabdominal Electrical Stimulation Did Not Change Oral-Rectal Transit Time in Piglets
Andre YF Tan, Magdy Sourial, John M Hutson, Bridget R Southwell
NEUROMODULATION | WILEY | Published : 2018
BACKGROUND: Transcutaneous electrical stimulation (TES) using interferential current (IFC) is a new therapeutic treatment for constipation. Clinical studies show that TES-IFC for 3-6 months improves colonic transit, but it is not clear if short-term stimulation affects transit or the effect requires longer to develop. The aim of this study was to determine if TES-IFC for only four days affects oral-rectal transit time in healthy pigs. METHODS: Twenty-two 4-5-week old large white female piglets had transit studies during week 4 and week 5 by placing a capsule containing 18 radiopaque plastic markers in the esophagus under anesthetic followed by x-rays at 6, 30, 54, and 78 hours. Animals were ..View full abstract
Awarded by Australian National Health and Medical Research Council (NHMRC)
This study was funded by the Australian National Health and Medical Research Council (NHMRC) Development Grant APP1000820 2010-2012 and Senior Research Fellowship (BS, 607396, 1023095), MCRI Theme Investment Funding and supported by the 'Victorian Government Operational Infrastructural Support Program'.