Journal article

Morbidity from in-hospital complications is greater than treatment failure in patients with Staphylococcus aureus bacteraemia

NE Holmes, JO Robinson, SJ van Hal, WJ Munckhof, E Athan, TM Korman, AC Cheng, JD Turnidge, PDR Johnson, BP Howden, J Owen Robinson

BMC Infectious Diseases | BMC | Published : 2018

Abstract

Background: Various studies have identified numerous factors associated with poor clinical outcomes in patients with Staphylococcus aureus bacteraemia (SAB). A new study was created to provide deeper insight into in-hospital complications and risk factors for treatment failure. Methods: Adult patients hospitalised with Staphylococcus aureus bacteraemia (SAB) were recruited prospectively into a multi-centre cohort. The primary outcome was treatment failure at 30 days (composite of all-cause mortality, persistent bacteraemia, or recurrent bacteraemia), and secondary measures included in-hospital complications and mortality at 6- and 12-months. Data were available for 222 patients recruited fro..

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