Journal article
Liberal glucose control in ICU patients with diabetes: A before-and-after study
N Luethi, L Cioccari, P Biesenbach, L Lucchetta, H Kagaya, R Morgan, F Di Muzio, B Presello, D Gaafar, A Hay, M Crisman, R Toohey, H Russell, NJ Glassford, GM Eastwood, EI Ekinci, AM Deane, R Bellomo, J Mårtensson
Critical Care Medicine | LIPPINCOTT WILLIAMS & WILKINS | Published : 2018
Abstract
Objectives: To assess the feasibility, biochemical efficacy, and safety of liberal versus conventional glucose control in ICU patients with diabetes. Design: Prospective, open-label, sequential period study. Setting: A 22-bed mixed ICU of a tertiary hospital in Australia. Patients: We compared 350 consecutive patients with diabetes admitted over 15 months who received liberal glucose control with a preintervention control population of 350 consecutive patients with diabetes who received conventional glucose control. Interventions: Liberal control patients received insulin therapy if glucose was greater than 14 mmol/L (target: 10-14 mmol/L [180-252 mg/dL]). Conventional control patients recei..
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Funding Acknowledgements
Supported, in part, by grants from the Austin Hospital Intensive Care Trust Fund. The Avant Doctors-In-Training Research Scholarship supported Dr. Glassford. Drs. Hay and Martensson's institution received funding from the Austin Hospital Intensive Care Trust Fund. Dr. Glassford received other support from AVANT Mutual, Doctors in Training, Scholarship 2014-2015 (paid research salary). The remaining authors have disclosed that they do not have any potential conflicts of interest.