Journal article
An acute, double-blind, placebo-controlled crossover study of 320 mg and 640 mg doses of a special extract of Bacopa monnieri (CDRI 08) on sustained cognitive performance
LA Downey, J Kean, F Nemeh, A Lau, A Poll, R Gregory, M Murray, J Rourke, B Patak, MP Pase, A Zangara, J Lomas, A Scholey, C Stough
Phytotherapy Research | WILEY | Published : 2013
DOI: 10.1002/ptr.4864
Abstract
Standardized extracts of the traditional Ayurvedic medicine Bacopa monnieri (BM) (Brahmi) have been recently shown to have cognitive enhancing effects in chronic administration studies. Pre-clinical work has also identified a number of acute anxiolytic, nootropic, and cardiovascular effects of BM. There has, however, been little research on the acute effects of BM on cognitive function. The current study aimed to assess the acute effects of a specific extract of BM (KeenMind® - CDRI 08) in a double-blind, placebo-controlled study in normal healthy participants who completed a cognitively demanding series of tests. Twenty-four healthy volunteers completed six repetitions of the Cognitive Dema..
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Awarded by Australian Research Council
Funding Acknowledgements
The study was funded by an Australian Research Council Discovery grant (DP1093825) to Prof Con Stough, Andrew Scholey, and Kevin Croft and funding from Soho Flordis International (SFI) who also provided the special extract of BM (CDRI 08) and placebo used in this study. Andrea Zangara is employed by SFI as Research and Development Director.