Journal article
Complexity and Distribution of Drivers in Relation to Duration of Persistent Atrial Fibrillation
HS Lim, M Hocini, R Dubois, A Denis, N Derval, S Zellerhoff, S Yamashita, B Berte, S Mahida, Y Komatsu, M Daly, L Jesel, C Pomier, V Meillet, S Amraoui, AJ Shah, H Cochet, F Sacher, P Jaïs, M Haïssaguerre
Journal of the American College of Cardiology | Published : 2017
Abstract
Background The underlying mechanisms sustaining human persistent atrial fibrillation (PsAF) is poorly understood. Objectives This study sought to investigate the complexity and distribution of AF drivers in PsAF of varying durations. Methods Of 135 consecutive patients with PsAF, 105 patients referred for de novo ablation of PsAF were prospectively recruited. Patients were divided into 3 groups according to AF duration: PsAF presenting in sinus rhythm (AF induced), PsAF 12 months. Patients wore a 252-electrode vest for body surface mapping. Localized drivers (re-entrant or focal) were identified using phase-mapping algorithms. Results In this patient cohort, the most prominent re-entrant dri..
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