Journal article

Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging

GW Albers, MP Marks, S Kemp, S Christensen, JP Tsai, S Ortega-Gutierrez, RA McTaggart, MT Torbey, M Kim-Tenser, T Leslie-Mazwi, A Sarraj, SE Kasner, SA Ansari, SD Yeatts, S Hamilton, M Mlynash, JJ Heit, G Zaharchuk, S Kim, J Carrozzella Show all

NEW ENGLAND JOURNAL OF MEDICINE | MASSACHUSETTS MEDICAL SOC | Published : 2018

Abstract

BACKGROUND: Thrombectomy is currently recommended for eligible patients with stroke who are treated within 6 hours after the onset of symptoms. METHODS: We conducted a multicenter, randomized, open-label trial, with blinded outcome assessment, of thrombectomy in patients 6 to 16 hours after they were last known to be well and who had remaining ischemic brain tissue that was not yet infarcted. Patients with proximal middle-cerebral-artery or internal-carotid-artery occlusion, an initial infarct size of less than 70 ml, and a ratio of the volume of ischemic tissue on perfusion imaging to infarct volume of 1.8 or more were randomly assigned to endovascular therapy (thrombectomy) plus standard m..

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University of Melbourne Researchers