Journal article

Importance of Early Weight Changes to Predict Long-Term Weight Gain During Psychotropic Drug Treatment

Frederik Vandenberghe, Mehdi Gholam-Rezaee, Nuria Saig-Morgui, Aurelie Delacretaz, Eva Choong, Alessandra Solida-Tozzi, Stephane Kolly, Jacques Thonney, Sylfa Fassassi Gallo, Ahmed Hedjal, Anne-Emmanuelle Ambresin, Armin von Gunten, Philippe Conus, Chin B Eap

JOURNAL OF CLINICAL PSYCHIATRY | PHYSICIANS POSTGRADUATE PRESS | Published : 2015

Abstract

BACKGROUND: Psychotropic drugs can induce substantial weight gain, particularly during the first 6 months of treatment. The authors aimed to determine the potential predictive power of an early weight gain after the introduction of weight gain-inducing psychotropic drugs on long-term weight gain. METHOD: Data were obtained from a 1-year longitudinal study ongoing since 2007 including 351 psychiatric (ICD-10) patients, with metabolic parameters monitored (baseline and/or 1, 3, 6, 9, 12 months) and with compliance ascertained. International Diabetes Federation and World Health Organization definitions were used to define metabolic syndrome and obesity, respectively. RESULTS: Prevalences of met..

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