Journal article

Childhood sexual and physical abuse: age at exposure modulates impact on functional outcome in early psychosis patients

L Alameda, C Ferrari, PS Baumann, M Gholam-Rezaee, KQ Do, P Conus

PSYCHOLOGICAL MEDICINE | CAMBRIDGE UNIV PRESS | Published : 2015

Abstract

BACKGROUND: Evidence suggests a relationship between exposure to trauma during childhood and functional impairments in psychotic patients. However, the impact of age at the time of exposure has been understudied in early psychosis (EP) patients. METHOD: Two hundred and twenty-five patients aged 18-35 years were assessed at baseline and after 2, 6, 18, 24, 30 and 36 months of treatment. Patients exposed to sexual and/or physical abuse (SPA) were classified according to age at the time of first exposure (Early SPA: before age 11 years; Late SPA: between ages 12 and 15 years) and then compared to patients who were not exposed to such trauma (Non-SPA). The functional level in the premorbid phase..

View full abstract

Grants

Awarded by Swiss National Science Foundation


Awarded by National Center of Competence in Research (NCCR) 'SYNAPSY - The Synaptic Bases of Mental Diseases' from the Swiss National Science Foundation


Funding Acknowledgements

We thank the Case Managers from Tipp Program for collecting these data and Martin Preisig for his mentorship. We thank our financial support: Swiss National Science Foundation (no. 320030_122419 to P.C. and K.Q.D.); National Center of Competence in Research (NCCR) 'SYNAPSY - The Synaptic Bases of Mental Diseases' from the Swiss National Science Foundation (no. 51AU40_125759 to KQD); Alamaya Foundation and Avina Stiftung. Most of all, we express our gratitude to all the patients for their enduring participation.