Evidence for a differential contribution of early perceptual and late cognitive processes during encoding to episodic memory impairment in schizophrenia
Amity E Green, Paul B Fitzgerald, Patrick J Johnston, Pradeep J Nathan, Jayashri Kulkarni, Rodney J Croft
WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY | TAYLOR & FRANCIS LTD | Published : 2017
OBJECTIVES: Schizophrenia is characterised by significant episodic memory impairment that is thought to be related to problems with encoding, however the neuro-functional mechanisms underlying these deficits are not well understood. The present study used a subsequent recognition memory paradigm and event-related potentials (ERPs) to investigate temporal aspects of episodic memory encoding deficits in schizophrenia. METHODS: Electroencephalographic data was recorded in 24 patients and 19 healthy controls whilst participants categorised single words as pleasant/unpleasant. ERPs were generated to subsequently recognised versus unrecognised words on the basis of a forced-choice recognition memo..View full abstract
Awarded by National Health and Medical Research Council
Awarded by NHMRC practitioner Fellowship
This study was funded by the National Health and Medical Research Council (Project Grant 502910). P.B.F. is supported by a NHMRC practitioner Fellowship (1078567).