Journal article

Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere

Benjamin A Chalmers, Hui Xing, Sevan Houston, Charlotte Clark, Sussan Ghassabian, Andy Kuo, Benjamin Cao, Andrea Reitsma, Cody-Ellen P Murray, Jeanette E Stok, Glen M Boyle, Carly J Pierce, Stuart W Littler, David A Winkler, Paul V Bernhardt, Cielo Pasay, James J De Voss, James McCarthy, Peter G Parsons, Gimme H Walter Show all

Angewandte Chemie International Edition | WILEY-V C H VERLAG GMBH | Published : 2016


Awarded by Australian Research Council

Funding Acknowledgements

This work was supported by the Australian Research Council (Future Fellowship to C.M.W., FT110100851), the University of Queensland, the CSIRO (Melbourne), NCRIS 2013 THD grant funding to the TIA-QLD Node from Therapeutic Innovation Australia (TIA), and infrastructure purchased using investment funds from the Queensland Government Smart State Research Facilities Fund as well as from Therapeutic Innovation Australia. We sincerely thank Michael Falkiner (CSIRO) for the supply of dimethylcubane-1,4-dicarboxylate. Furthermore, we acknowledge Dani Cardozo (CSIRO) for assistance with the SAHA-related animal work and Prof. Anders Woetmann (University of Copenhagen) for kindly supplying the MyLa2059 cell line. Dr. Greg Daglish (Department of Agriculture and Fisheries) kindly provided the Tribolium castaneum material for use in tests. The Australian Regenerative Medicine Institute is supported by grants from the State Government of Victoria and the Australian Government.