Journal article

Reducing sedentary time and fat mass may improve glucose tolerance and insulin sensitivity in adults surviving 6 months after stroke: A phase I pilot study

KN Borschmann, EI Ekinci, S Iuliano, L Churilov, MYC Pang, J Bernhardt

European Stroke Journal | SAGE PUBLICATIONS LTD | Published : 2017

Abstract

Introduction: Deranged glycaemic control is common post-stroke, increasing risks of recurrent stroke and development of diabetes. The aim of the study is to examine glucose metabolism in relation to body composition, physical activity and sedentary time post-stroke. Patients and methods: Observational study: Non-diabetic adults, unable to walk independently, were recruited within 2 weeks of first stroke. Primary outcome: 2-h glucose level (mmol/l, oral glucose tolerance test), assessed at baseline and 6 months. Homeostasis Model Assessment of Insulin Sensitivity, total body fat and lean mass (dual energy X-ray absorptiometry), sedentary time (lying or sitting), standing and walking (PAL2 acc..

View full abstract

Grants

Awarded by Australian Research Council


Awarded by NHMRC Early Career Research Fellowship


Funding Acknowledgements

The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This study was funded by the Australian Research Council (ARCFT09901086), Austin Health Medical Research Fund and LaTrobe University Faculty Research Grant. EIE was supported by an NHMRC Early Career Research Fellowship (#1054312), Viertel Clinical Investigatorship, Sir Edward Weary Dunlop Medical Research Foundation grant and RACP fellowship. JB was supported by an NHMRC Established Researcher Fellowship. KB was supported by a La Trobe University Postgraduate Research Scholarship.