Journal article
Safety studies for a 44-channel suprachoroidal retinal prosthesis: A chronic passive study
CJ Abbott, DAX Nayagam, CD Luu, SB Epp, RA Williams, CM Salinas-LaRosa, J Villalobos, C McGowan, MN Shivdasani, O Burns, J Leavens, J Yeoh, AA Brandli, PC Thien, J Zhou, H Feng, CE Williams, RK Shepherd, PJ Allen
Investigative Ophthalmology and Visual Science | ASSOC RESEARCH VISION OPHTHALMOLOGY INC | Published : 2018
Open access
Abstract
PURPOSE. Following successful clinical outcomes of the prototype suprachoroidal retinal prosthesis, Bionic Vision Australia has developed an upgraded 44-channel suprachoroidal retinal prosthesis to provide a wider field of view and more phosphenes. The aim was to evaluate the preclinical passive safety characteristics of the upgraded electrode array. METHODS. Ten normal-sighted felines were unilaterally implanted with an array containing platinum electrodes (44 stimulating and 2 returns) on a silicone carrier near the area centralis. Clinical assessments (color fundus photos, optical coherence tomography, full-field electroretinography, intraocular pressure) were performed under anesthesia p..
View full abstractGrants
Awarded by Australian Research Council
Funding Acknowledgements
[ "The authors thank the following people for their respective contributions: Vanessa Maxim and Tara Lofhelm (Bionics Institute) for device fabrication, Tamara Brawn (Bionic Vision Australia, BVA) and BVA staff for administrative support, Fenella Long and Sue Peirce (St. Vincent's Hospital Melbourne) for veterinary advice, and the staff of the Biological Research Centre (University of Melbourne) and the Experimental Medical and Surgical Research Unit (St. Vincent's Hospital Melbourne) for support with animal care.", "Supported by the ARC Special Research Initiative in Bionic Vision Science and Technology grant to Bionic Vision Australia (RKS; Canberra, ACT, Australia); National Health and Medical Research Council (NHMRC) Grant 1082358 (PJA; Canberra, ACT, Australia); NHMRC Grant 1063093 (MNS). The Bionics Institute and the Centre for Eye Research Australia wish to acknowledge the support of the Victorian Government through its Operational Infrastructure Support Program (VIC, Australia)." ]