Journal article
Determinants of Ligand Subtype-Selectivity at alpha(1A)-Adrenoceptor Revealed Using Saturation Transfer Difference (STD) NMR
Kelvin J Yong, Tasneem M Vaid, Patrick J Shilling, Feng-Jie Wu, Lisa M Williams, Mattia Deluig, Andreas Plueckthun, Ross AD Bathgate, Paul R Gooley, Daniel J Scott
ACS Chemical Biology | AMER CHEMICAL SOC | Published : 2018
Grants
Awarded by NHMRC
Awarded by ARC
Awarded by Schweizerischer Nationalfonds
Funding Acknowledgements
We thank V. Jameson and J. Kie (MBC Flow Cytometry Facility) for assistance with FAGS, as well as S. Layfield, T. Ferraro, and M. Petrovska for cell-based assays and R Cridge and L. C. Cardinal for assistance with characterizing the purified alpha<INF>1</INF>-ARs (all from The Florey Institute of Neuroscience and Mental Health). This work was supported by NHMRC project grants 1081801 (D.J.S) and 1081844 (R.A.D.B, P.R.G, D.J.S); ARC equipment grant LE120100022. D.J.S. is an NHMRC Boosting Dementia Research Leadership Fellow. R.A.D.B. is an NHMRC Senior Research Fellow. Studies at The Florey Institute of Neuroscience and Mental Health were supported by the Victorian Government's Operational Infrastructure Support Program. Studies at the University of Zurich were supported by Schweizerischer Nationalfonds grant 31003A_153143 (to A.P.).