Journal article

Impact of Incidence and Progression of Diabetic Retinopathy on Vision-Specific Functioning

Preeti Gupta, Alfred Tau Liang Gan, Ryan Eyn Kidd Man, Eva K Fenwick, Neelam Kumari, Gavin Tan, Paul Mitchell, Charumathi Sabanayagam, Tien Yin Wong, Ching-Yu Cheng, Ecosse L Lamoureux

Ophthalmology | ELSEVIER SCIENCE INC | Published : 2018


PURPOSE: To investigate the independent impact of the incidence and progression of diabetic retinopathy (DR) on visual functioning (VF). DESIGN: Population-based cohort study. PARTICIPANTS: A total of 518 participants aged 40 to 80 years (baseline visit 2007-2009 and second visit 6 years later, 2013-2015), with diabetes, clinical data, and VF information at both visits. MAIN OUTCOME MEASURES: VF-7 scores, converted to interval-level person measures (in logits) using Rasch analysis. METHODS: Incident DR was defined using the Modified Airlie House classification as "none or minimal" DR at baseline and at least mild nonproliferative DR at follow-up; incident vision-threatening DR (VTDR; severe ..

View full abstract


Awarded by National Medical Research Council (Singapore)

Funding Acknowledgements

The author(s) have made the following disclosure(s): The Singapore Indian Eye Study was funded by the National Medical Research Council (Singapore), grant no. NMRC/1371/2013. The grant body had no roles in design, conduct, or data analysis of the study, nor in manuscript preparation and approval.