Journal article
Negligible impact of mass screening and treatment on mesoendemic malaria transmission at west timor in eastern Indonesia: A cluster-randomized trial
I Sutanto, A Kosasih, IRF Elyazar, DR Simanjuntak, TA Larasati, MS Dahlan, I Wahid, I Mueller, C Koepfli, R Kusriastuti, A Surya, FJ Laihad, WA Hawley, FH Collins, JK Baird, NF Lobo
Clinical Infectious Diseases | OXFORD UNIV PRESS INC | Published : 2018
DOI: 10.1093/cid/ciy231
Abstract
Background Mass screening and treatment (MST) aims to reduce malaria risk in communities by identifying and treating infected persons without regard to illness. Methods A cluster-randomized trial evaluated malaria incidence with and without MST. Clusters were randomized to 3, 2, or no MST interventions: MST3, 6 clusters (156 households/670 individuals); MST2, 5 clusters (89 households/423 individuals); and MST0, 5 clusters (174 households/777 individuals). All clusters completed the study with 14 residents withdrawing. In a cohort of 324 schoolchildren (MST3, n = 124; MST2, n = 57; MST0, n = 143) negative by microscopy at enrollment, we evaluated the incidence density of malaria during 3 mon..
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Awarded by Bill & Melinda Gates Foundations
Funding Acknowledgements
This project has been funded in whole or in part with funds from the Bill & Melinda Gates Foundations (grant number 45114).