Journal article
Lack of multiple copies of pfmdr1 gene in Papua New Guinea
Eva Maria Hodel, Jutta Marfurt, Dania Mueller, Anja Rippert, Steffen Borrmann, Ivo Mueller, John C Reeder, Peter Siba, Blaise Genton, Hans-Peter Beck
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | ELSEVIER SCIENCE INC | Published : 2008
Abstract
We describe here the results of an analysis of Plasmodium falciparum multidrug resistance protein 1 (pfmdr1) gene copy number from 440 field isolates from Papua New Guinea. No multiple copies of the gene were found, which corresponds to the lack of usage of mefloquine. These data extend regional knowledge about the distribution of multidrug-resistant P. falciparum.