Journal article
Rationale and design of the Kanyini guidelines adherence with the polypill (Kanyini-GAP) study: A randomised controlled trial of a polypill-based strategy amongst Indigenous and non Indigenous people at high cardiovascular risk
H Liu, A Patel, A Brown, S Eades, N Hayman, S Jan, I Ring, G Stewart, A Tonkin, T Weeramanthri, V Wade, A Rodgers, T Usherwood, B Neal, D Peiris, H Burke, C Reid, A Cass
BMC Public Health | BMC | Published : 2010
Abstract
Background. The Kanyini Guidelines Adherence with the Polypill (Kanyini-GAP) Study aims to examine whether a polypill-based strategy (using a single capsule containing aspirin, a statin and two blood pressure-lowering agents) amongst Indigenous and non-Indigenous people at high risk of experiencing a cardiovascular event will improve adherence to guideline-indicated therapies, and lower blood pressure and cholesterol levels. Methods/Design. The study is an open, randomised, controlled, multi-centre trial involving 1000 participants at high risk of cardiovascular events recruited from mainstream general practices and Aboriginal Medical Services, followed for an average of 18 months. The parti..
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Funding Acknowledgements
The Kanyini GAP Study is an investigator-initiated and conducted study, funded by a primary health care project grant (#457508), a health services program grant (#402797) and a project grant (#632810) from the Australian National Health & Medical Research Council (NHMRC). AC and AP are funded by Senior Research Fellowships from the NHMRC. AB is funded by an Indigenous post-doctoral fellowship from the National Heart Foundation. SJ is funded by an NHMRC Career Development Award. We thank Dr Peter Arnold for his assistance in the preparation of this paper.