Melatonin enhances antioxidant molecules in the placenta, reduces secretion of soluble fms-like tyrosine kinase 1 (sFLT) from primary trophoblast but does not rescue endothelial dysfunction: An evaluation of its potential to treat preeclampsia

Natalie J Hannan; Natalie K Binder; Sally Beard; Nguyen Tuong-Vi; Tu'uhevaha J Kaitu'u-Lino; Stephen Tong

Journal article

Melatonin enhances antioxidant molecules in the placenta, reduces secretion of soluble fms-like tyrosine kinase 1 (sFLT) from primary trophoblast but does not rescue endothelial dysfunction: An evaluation of its potential to treat preeclampsia

Natalie J Hannan, Natalie K Binder, Sally Beard, Nguyen Tuong-Vi, Tu'uhevaha J Kaitu'u-Lino, Stephen Tong

PLOS ONE | PUBLIC LIBRARY SCIENCE | Published : 2018

DOI: 10.1371/journal.pone.0187082

University of Melbourne Researchers

Tu'Uhevaha Lino Author Obstetrics and Gynaecology Royal Women's Hospital/Mercy

Stephen Tong Author Obstetrics and Gynaecology Royal Women's Hospital/Mercy

Vi Nguyen Author Obstetrics and Gynaecology Royal Women's Hospital/Mercy

Natalie Hannan Author Obstetrics and Gynaecology Royal Women's Hospital/Mercy

Sally Beard Author Obstetrics and Gynaecology Royal Women's Hospital/Mercy

Grants

Awarded by National Health and Medical Research Council of Australia (NHMRC)

Funding Acknowledgements

The National Health and Medical Research Council of Australia (NHMRC) provided salary support (#1050765 to ST; #1062418 to TKL). NJH salary was supported by a University of Melbourne CR Roper Fellowship. The funders had no role in study design, data collection, analysis or decision to publish.