Journal article
Trawler Web: An online de novo motif discovery tool for next-generation sequencing datasets
LT Dang, M Tondl, MHH Chiu, J Revote, B Paten, V Tano, A Tokolyi, F Besse, G Quaife-Ryan, H Cumming, MJ Drvodelic, MP Eichenlaub, JC Hallab, JS Stolper, FJ Rossello, MA Bogoyevitch, DA Jans, HT Nim, ER Porrello, JE Hudson Show all
BMC Genomics | BMC | Published : 2018
Abstract
Background: A strong focus of the post-genomic era is mining of the non-coding regulatory genome in order to unravel the function of regulatory elements that coordinate gene expression (Nat 489:57-74, 2012; Nat 507:462-70, 2014; Nat 507:455-61, 2014; Nat 518:317-30, 2015). Whole-genome approaches based on next-generation sequencing (NGS) have provided insight into the genomic location of regulatory elements throughout different cell types, organs and organisms. These technologies are now widespread and commonly used in laboratories from various fields of research. This highlights the need for fast and user-friendly software tools dedicated to extracting cis-regulatory information contained i..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
This work was supported by an Australian Research Council Discovery Project grant (DP1049980), a National Health and Medical Research Council/Heart Foundation Career Development Fellowship (1049980), Sun Foundation to MR and UROP scholarships to LTD, MHHC, MJD and AT. The Australian Regenerative Medicine Institute is supported by grants from the State Government of Victoria and the Australian Government. This research was supported by use of the Nectar Research Cloud, a collaborative Australian research platform supported by the National Collaborative Research Infrastructure Strategy (NCRIS).