Journal article

Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK alpha 2 beta 2 gamma 1 by the Glucose Importagog SC4

Kevin RW Ngoei, Christopher G Langendorf, Naomi XY Ling, Ashfaqul Hoque, Swapna Varghese, Michelle A Camerino, Scott R Walker, Ylva E Bozikis, Toby A Dite, Ashley J Ovens, William J Smiles, Roxane Jacobs, He Huang, Michael W Parker, John W Scott, Mark H Rider, Richard C Foitzik, Bruce E Kemp, Jonathan B Baell, Jonathan S Oakhill

Cell Chemical Biology | CELL PRESS | Published : 2018


Awarded by Australian Research Council (ARC)

Awarded by National Health and Medical Research Council (NHMRC)

Awarded by Jack Brockhoff foundation

Funding Acknowledgements

This research was undertaken on the MX2 beamline at the Australian Synchrotron, Victoria, Australia, part of ANSTO, and made use of the ACRF detector. We thank the beamline staff for their assistance. We thank Sandra Galic and Lisa Murray-Segal for assistance with preparation of primary hepatocytes and isolation of mouse muscles. This work was supported by grants from the Australian Research Council (ARC ID: 130100988) and the National Health and Medical Research Council (NHMRC ID: 1098459, 1145265). C.G.L. is an EH Flack Fellow and is supported by the Jack Brockhoff foundation (JBF-4206, 2016). M.W.P., B.E.K., and J.B.B. are NHMRC Research Fellows. J.S.O. is an ARC Future Fellow. This study was supported in part by the Victorian Government's Operational Infrastructure Support Program.