Journal article
Early life predictors of brain development at term-equivalent age in infants born across the gestational age spectrum
DK Thompson, CE Kelly, J Chen, R Beare, B Alexander, ML Seal, K Lee, LG Matthews, PJ Anderson, LW Doyle, AJ Spittle, JLY Cheong
Neuroimage | ACADEMIC PRESS INC ELSEVIER SCIENCE | Published : 2019
Abstract
Background: It is well established that preterm infants have altered brain development compared with full-term (FT; ≥37 weeks' gestational age [GA]) infants, however the perinatal factors associated with brain development in preterm infants have not been fully elucidated. In particular, perinatal predictors of brain development may differ between very preterm infants (VP; <32 weeks' GA) and infants born moderate (MP; 32–33 weeks' GA) and late (LP; 34–36 weeks' GA) preterm, but this has not been studied. This study aimed to investigate the effects of early life predictors on brain volume and microstructure at term-equivalent age (TEA; 38–44 weeks), and whether these effects differ for GA grou..
View full abstractGrants
Awarded by Murdoch Children's Research Institute
Funding Acknowledgements
We gratefully acknowledge support from members of the Victorian Infant Brain Studies (VIBeS) group, Developmental Imaging group, and Melbourne Children's MRI Centre at the Murdoch Children's Research Institute, and thank the families who participated in the study. This work was supported in part by the Australian National Health and Medical Research Council (NHMRC) (Project Grant 1028822 and 1024516; Centre of Clinical Research Excellence Grant 546519; Centre of Research Excellence Grant 1060733; Senior Research Fellowship 1081288 to P.J.A.; Early Career Fellowship 1053787 to J.L.Y.C., 1053767 to A.J.S., 1012236 to D.K.T.; Career Development Fellowship 1108714 to A.J.S., 1085754 to D.K.T.), Murdoch Children's Research Institute Clinical Sciences Theme Grant, the Royal Children's Hospital, the Department of Paediatrics at the University of Melbourne, the Victorian Government Operational Infrastructure Support Program, and The Royal Children's Hospital Foundation.