Dynamic CT for parathyroid adenoma detection: How does radiation dose compare with nuclear medicine?

Abstract

OBJECTIVE. Dynamic CT is increasingly used for preoperative localization of parathyroid adenomas, but concerns remain about the radiation effective dose of CT compared with that of 99m Tc-sestamibi scintigraphy. The purpose of this study was to compare the radiation dose delivered by three-phase dynamic CT with that delivered by 99m Tc-sestamibi SPECT/CT performed in accordance with our current protocols and to assess the possible reduction in effective dose achieved by decreasing the scan length (i.e., z-axis) of two phases of the dynamic CT protocol. MATERIALS AND METHODS. The effective dose of a 99m Tc-sestamibi nuclear medicine parathyroid study performed with and without coregistration ..