Journal article

A Modeling Study of the Cost-Effectiveness of a Risk-Stratified Surveillance Program for Melanoma in the United Kingdom

Edward CF Wilson, Juliet A Usher-Smith, Jon Emery, Pippa Corrie, Fiona M Walter



BACKGROUND: Population-wide screening for melanoma is unlikely to be cost-effective. Nevertheless, targeted surveillance of high-risk individuals may be. OBJECTIVES: To estimate the cost-effectiveness of various surveillance strategies in the UK population, stratified by risk using a simple self-assessment tool scoring between 0 and 67. METHODS: A decision model comparing alternative surveillance policies from the perspective of the UK National Health Service over 30 years was developed. The strategy with the highest expected net benefit for each risk score was identified, resulting in a compound risk-stratified policy describing the most cost-effective population-wide strategy. The overall ..

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Awarded by F. M. Walter's Clinician Scientist Award from the National Institute for Health Research (NIHR)

Awarded by National Institute for Health Research

Funding Acknowledgements

This study was supported in part by F. M. Walter's Clinician Scientist Award from the National Institute for Health Research (NIHR) (grant no. RG 68235). E. C. F. Wilson is funded by the NIHR Cambridge Biomedical Research Centre. J. Usher-Smith was funded by an NIHR Clinical Lectureship. J. Emery is funded by an National Health and Medical Research Council (NHMRC) Practitioner Fellowship. The analysis was performed using the Darwin Supercomputer of the University of Cambridge High Performance Computing Service (, provided by Dell, Inc., using Strategic Research Infrastructure Funding from the Higher Education Funding Council for England and funding from the Science and Technology Facilities Council. Views expressed in this publication are those of the authors and not necessarily those of the NHS, the NIHR, or the Department of Health.