T Cell LEGO: Identifying the Master Builders and What They Do.
Jasmine Li, Stephen J Turner
Immunity | Published : 2018
Understanding how cell fate decisions are made during cellular differentiation and the mechanisms that drive them is a holy grail of cell biology. In this issue of Immunity, Hu et al. (2018) and Johnson et al. (2018) demonstrate that key transcriptional regulators and global changes in nuclear architecture underlie differentiation decisions during T cell development.