Journal article

No evidence of white adipocyte browning after endurance exercise training in obese men

T Tsiloulis, AL Carey, J Bayliss, B Canny, RCR Meex, MJ Watt

International Journal of Obesity | NATURE PUBLISHING GROUP | Published : 2018

Abstract

BACKGROUND/OBJECTIVES: The phenomenon of adipocyte 'beiging' involves the conversion of non-classic brown adipocytes to brown-like adipose tissue with thermogenic, fat-burning properties, and this phenomenon has been shown in rodents to slow the progression of obesity-associated metabolic diseases. Rodent studies consistently report adipocyte beiging after endurance exercise training, indicating that increased thermogenic capacity in these adipocytes may underpin the improved health benefits of exercise training. The aim of this study was to determine whether prolonged endurance exercise training induces beige adipogenesis in subcutaneous adipose tissues of obese men. SUBJECTS/METHODS: Molec..

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Grants

Awarded by National Health and Medical Research Council of Australia (NHMRC)


Awarded by NHMRC


Funding Acknowledgements

We thank Professor Ken Ho (University of Queensland) for the brown adipose tissue sample. This work was supported by the National Health and Medical Research Council of Australia (NHMRC, APP1098972) and MJW is supported by a Senior Research Fellowship from the NHMRC (APP1077703).