A systematic review and consensus definitions for standardised end-points in perioperative medicine: pulmonary complications

TEF Abbott; AJ Fowler; P Pelosi; M Gama de Abreu; AM Moller; J Canet; B Creagh-Brown; M Mythen; T Gin; MM Lalu; E Futier; MP Grocott; MJ Schultz; RM Pearse

Journal article

A systematic review and consensus definitions for standardised end-points in perioperative medicine: pulmonary complications

TEF Abbott, AJ Fowler, P Pelosi, M Gama de Abreu, AM Moller, J Canet, B Creagh-Brown, M Mythen, T Gin, MM Lalu, E Futier, MP Grocott, MJ Schultz, RM Pearse

BRITISH JOURNAL OF ANAESTHESIA | ELSEVIER SCI LTD | Published : 2018

DOI: 10.1016/j.bja.2018.02.007

Abstract

Background There is a need for robust, clearly defined, patient-relevant outcome measures for use in randomised trials in perioperative medicine. Our objective was to establish standard outcome measures for postoperative pulmonary complications research. Methods A systematic literature search was conducted using MEDLINE, Web of Science, SciELO, and the Korean Journal Database. Definitions were extracted from included manuscripts. We then conducted a three-stage Delphi consensus process to select the optimal outcome measures in terms of methodological quality and overall suitability for perioperative trials. Results From 2358 records, the full texts of 81 manuscripts were retrieved, of which ..

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University of Melbourne Researchers

David Story Author

Kate Leslie Author

Bernhard Riedel Author

Lis Evered Author

Grants

Funding Acknowledgements

The Standardized Endpoints for Perioperative Medicine (StEP) Collaborative is supported by an unrestricted grant from the British Journal of Anaesthesia. T.E.F.A. was supported by a Medical Research Council and British Journal of Anaesthesia Clinical Research Training Fellowship. R.M.P. is a National Institute for Health Research (UK) Professor.