A systematic review and consensus definitions for standardised end-points in perioperative medicine: pulmonary complications
TEF Abbott, AJ Fowler, P Pelosi, M Gama de Abreu, AM Moller, J Canet, B Creagh-Brown, M Mythen, T Gin, MM Lalu, E Futier, MP Grocott, MJ Schultz, RM Pearse
BRITISH JOURNAL OF ANAESTHESIA | ELSEVIER SCI LTD | Published : 2018
Background There is a need for robust, clearly defined, patient-relevant outcome measures for use in randomised trials in perioperative medicine. Our objective was to establish standard outcome measures for postoperative pulmonary complications research. Methods A systematic literature search was conducted using MEDLINE, Web of Science, SciELO, and the Korean Journal Database. Definitions were extracted from included manuscripts. We then conducted a three-stage Delphi consensus process to select the optimal outcome measures in terms of methodological quality and overall suitability for perioperative trials. Results From 2358 records, the full texts of 81 manuscripts were retrieved, of which ..View full abstract
The Standardized Endpoints for Perioperative Medicine (StEP) Collaborative is supported by an unrestricted grant from the British Journal of Anaesthesia. T.E.F.A. was supported by a Medical Research Council and British Journal of Anaesthesia Clinical Research Training Fellowship. R.M.P. is a National Institute for Health Research (UK) Professor.