Immunological responses following administration of a genotype 1a/1b/2/3a quadrivalent HCV VLP vaccine

D Christiansen; L Earnest-Silveira; B Chua; P Meuleman; I Boo; B Grubor-Bauk; DC Jackson; ZY Keck; SKH Foung; HE Drummer; EJ Gowans; J Torresi

Journal article

Immunological responses following administration of a genotype 1a/1b/2/3a quadrivalent HCV VLP vaccine

D Christiansen, L Earnest-Silveira, B Chua, P Meuleman, I Boo, B Grubor-Bauk, DC Jackson, ZY Keck, SKH Foung, HE Drummer, EJ Gowans, J Torresi

Scientific Reports | NATURE PUBLISHING GROUP | Published : 2018

DOI: 10.1038/s41598-018-24762-9

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University of Melbourne Researchers

Heidi Drummer Author Microbiology and Immunology

Joseph Torresi Author Microbiology and Immunology

Linda Earnest Author Microbiology and Immunology

David Jackson Author Microbiology and Immunology

Brendon Chua Author Microbiology and Immunology

Related Projects (2)

HEPATITIS C VACCINE

Hepatitis C virus is responsible for over 300,000 deaths per year world wide and in Australia causes 10,000 new cases each year. A vaccine t..

DEVELOPING A QUADRIVALENT HCV VACCINE

A vaccine for hepatitis C virus (HCV) is not yet available. Immune responses that are able to protect against infection are possible, making..

Grants

Awarded by National Health and Medical Research Council (NHMRC) of Australia

Awarded by National Institute of Allergy and Infectious Diseases/NIH

Awarded by NHMRC

Awarded by NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES

Funding Acknowledgements

This work was supported by the National Health and Medical Research Council (NHMRC) of Australia, grant numbers 1060436 and 1126379 and National Institute of Allergy and Infectious Diseases/NIH grants R21AI26582, U19AI123862 and R01AI132213 to SKHF. JT is supported by an NHMRC Practitioner Fellowship, number 106043. We wish to thank Prof Saumitra Das for having provided the cDNA for the production of the HCV genotype 3a VLP vaccine.