Health consequences for mother and baby of substantial pre-conception weight loss in obese women: study protocol for a randomized controlled trial
Sarah Price, Alison Nankervis, Michael Permezel, Luke Prendergast, Priya Sumithran, Joseph Proietto
TRIALS | BMC | Published : 2018
BACKGROUND: Current guidelines for the management of obesity in women planning pregnancy suggest lifestyle modification before conception. However, there is little evidence that lifestyle modification alters pregnancy outcomes. Bariatric surgery results in significant weight loss. This appears to reduce the risk of adverse pregnancy outcomes for the mother but may increase the risk of adverse outcomes for the infant. In order to reduce the risks of obesity-related adverse pregnancy outcomes for both mother and offspring, alternative approaches to the management of obesity in women planning pregnancy are needed. METHODS/DESIGN: This study, a two-arm, parallel group, randomized control trial, ..View full abstract
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The study is funded by the University of Melbourne and competitive funding obtained from the Norman Beischer Medical Research Foundation. SP is supported by a NHMRC post-graduate scholarship.