Journal article
Grip Strength Is Associated with Cognitive Performance in Schizophrenia and the General Population: A UK Biobank Study of 476559 Participants
J Firth, B Stubbs, D Vancampfort, JA Firth, M Large, S Rosenbaum, M Hallgren, PB Ward, J Sarris, AR Yung
Schizophrenia Bulletin | OXFORD UNIV PRESS | Published : 2018
Abstract
Background Handgrip strength may provide an easily-administered marker of cognitive functional status. However, further population-scale research examining relationships between grip strength and cognitive performance across multiple domains is needed. Additionally, relationships between grip strength and cognitive functioning in people with schizophrenia, who frequently experience cognitive deficits, has yet to be explored. Methods Baseline data from the UK Biobank (2007-2010) was analyzed; including 475397 individuals from the general population, and 1162 individuals with schizophrenia. Linear mixed models and generalized linear mixed models were used to assess the relationship between gri..
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Awarded by King’s College London
Funding Acknowledgements
J.F. is supported by a Blackmores Institute Fellowship and an MRC Doctoral Training Grant (P117413F07). J.S. is funded by an NHMRC Research Fellowship (APP1125000). B.S. is supported by the National Institute for Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care South London at King's College Hospital NHS Foundation Trust. B.S. is also part funded by the National Institute for Health Research (NIHR) Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London. S.R. is funded by an NHMRC Early Career Fellowship (APP1123336).