Journal article

External Validation of the PediBIRN Clinical Prediction Rule for Abusive Head Trauma

Helena Pfeiffer, Anne Smith, Alison Mary Kemp, Laura Elizabeth Cowley, John A Cheek, Stuart R Dalziel, Meredith L Borland, Sharon O'Brien, Megan Bonisch, Jocelyn Neutze, Ed Oakley, Louise Crowe, Stephen JC Hearps, Mark D Lyttle, Silvia Bressan, Franz E Babl

Pediatrics | AMER ACAD PEDIATRICS | Published : 2018

Abstract

BACKGROUND AND OBJECTIVES: A 4-variable abusive head trauma (AHT) clinical prediction rule (CPR) for use in the PICU was derived and validated for children <3 years of age by the Pediatric Brain Injury Research Network (PediBIRN). We aimed to externally validate PediBIRN as designed (PICU only) as well as using broader inclusion criteria (admitted children with head injuries). METHODS: This was a secondary analysis of a prospective multicenter study of pediatric head injuries at 5 Australian and New Zealand tertiary pediatric centers. Possible AHT was identified by clinician suspicion, epidemiology codes, or a high-risk group (<3 years of age, admitted, abnormal neuroimaging results). At 1 c..

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Grants

Awarded by National Health and Medical Research Council, Canberra, Australia


Awarded by National Health and Medical Research Council (Centre of Research Excellence for Pediatric Emergency Medicine), Canberra, Australia


Awarded by Emergency Medicine Foundation, Brisbane, Australia


Awarded by Perpetual Philanthropic Services, Australia


Awarded by Auckland Medical Research Foundation


Awarded by Health Research Council of New Zealand


Funding Acknowledgements

Funded by grants from the National Health and Medical Research Council (project grant GNT1046727, Centre of Research Excellence for Pediatric Emergency Medicine GNT1058560), Canberra, Australia; the Murdoch Children's Research Institute, Melbourne, Australia; the Emergency Medicine Foundation (EMPJ-11162), Brisbane, Australia; Perpetual Philanthropic Services (2012/1140), Australia; the Auckland Medical Research Foundation (3112011) and the A + Trust (Auckland District Health Board), Auckland, New Zealand; the Western Australia Health Targeted Research Funds 2013, Perth, Australia; and the Townsville Hospital and Health Service Private Practice Research and Education Trust Fund, Townsville, Australia; and supported by the Victorian Government's Infrastructure Support Program, Melbourne, Australia. Dr Babl's time was partially funded by a grant from The Royal Children's Hospital Foundation and the Melbourne Campus Clinician Scientist Fellowship, Melbourne, Australia, and a National Health and Medical Research Council Practitioner Fellowship, Canberra, Australia. Dr Dalziel's time was partially funded by the Health Research Council of New Zealand (HRC13/556).