Effect of Glutathione Bio-Molecule on Tooth Discoloration Associated with Silver Diammine Fluoride
Mahmoud Sayed, Naoko Matsui, Noriko Hiraishi, Toru Nikaido, Michael F Burrow, Junji Tagami
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | MDPI | Published : 2018
This study evaluated the effect of Glutathione (GSH) bio-molecule on the reduction of enamel and dentin discoloration after application of 38% silver diammine fluoride solution (SDF). One hundred and twenty bovine teeth specimens were used. The enamel and dentin specimens were divided into three groups: (1) SDF only (control); (2) SDF followed by application of a potassium iodide solution (KI); and (3) SDF mixed with 20% GSH. Half the specimens were exposed to light and the remainder kept in dark conditions (n = 10) Color changes were measured using a spectrophotometer at the following time intervals: before solution application (baseline) and immediately after application, then 3, 6, 24, 48..View full abstract
Awarded by Japan Society for the Promotion of Sciences
The authors thank Ahmed Abdou for his statistical support. This research was supported by the Japan Society for the Promotion of Sciences (16H05515).