Journal article
Subclinical device-detected atrial fibrillation and stroke risk: A systematic review and meta-analysis
R Mahajan, T Perera, AD Elliott, DJ Twomey, S Kumar, DA Munwar, KB Khokhar, A Thiyagarajah, ME Middeldorp, CJ Nalliah, JML Hendriks, JM Kalman, DH Lau, P Sanders
European Heart Journal | OXFORD UNIV PRESS | Published : 2018
Abstract
Aims To determine stroke risk in subclinical atrial fibrillation (AF) and temporal association between subclinical AF and stroke. Methods and results Pubmed/Embase was searched for studies reporting stroke in subclinical AF in patients with cardiac implantable electronic devices (CIEDs). After exclusions, 11 studies were analysed. Of these seven studies reported prevalence of subclinical AF, two studies reported association between subclinical and clinical AF, seven studies reported stroke risk in subclinical AF, and five studies reported temporal relationship between subclinical AF and stroke. Subclinical AF was noted after CIEDs implant in 35% [interquartile range (IQR) 34-42] of unselecte..
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Funding Acknowledgements
This study was supported by funds from the Centre of Heart Rhythm Disorders at the University of Adelaide. R.M. is supported by an Early Career Fellowship from the National Health and Medical Research Council of Australia and National Heart Foundation. S.K., A.M. and M.M. are supported by the Robert J. Craig Scholarship from the University of Adelaide. A.M. is supported by the Indonesia Endowment Fund for Education, Ministry of Finance, The Republic of Indonesia. K.K. is supported by Asia Pacific Heart Rhythm Society (APH RS) and New Zealand Heart Foundation (NZHF) overseas fellowship scholarship. AT. is supported by an APA Scholarship from the University of Adelaide. M.M and C.N. are supported by Postgraduate Scholarships funded by the National Health and Medical Research Council of Australia, C.N. is supported by the National Heart Foundation and by the BJ Amos Travelling Fellowship from the Westmead Association. J.H. is supported by an Early Career Fellowship from the National Heart Foundation of Australia and by the Derek Frewin Lectureship from the University of Adelaide. J.K. and P.S. are supported by Practitioner Fellowships from the National Health and Medical Research Council of Australia. D.L. is supported by the Robert J. Craig Lectureship from the University of Adelaide. P.S. is supported by the National Heart Foundation of Australia.