Journal article

Systematic review and consensus definitions for standardised endpoints in perioperative medicine: postoperative cancer outcomes

DJ Buggy, J Freeman, MZ Johnson, K Leslie, B Riedel, DI Sessler, A Kurz, V Gottumukkala, T Short, N Pace, PM Myles

British Journal of Anaesthesia | ELSEVIER SCI LTD | Published : 2018


BACKGROUND: The Standardising Endpoints for Perioperative Medicine group was established to derive an appropriate set of endpoints for use in clinical trials related to anaesthesia and perioperative medicine. Anaesthetic or analgesic technique during cancer surgery with curative intent may influence the risk of recurrence or metastasis. However, given the current equipoise in the existing literature, prospective, randomised, controlled trials are necessary to test this hypothesis. As such, a cancer subgroup was formed to derive endpoints related to research in onco-anaesthesia based on a current evidence base, international consensus and expert guidance. METHODS: We undertook a systematic re..

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